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receptor theory
Receptor theory is the application of receptor models to explain drug behavior. Pharmacological receptor models preceded accurate knowledge of receptors by many years.〔 〕 John Newport Langley and Paul Ehrlich introduced the concept of a receptor that would mediate drug action at the beginning of the 20th century. A J Clark was the first to quantify drug-induced biological responses (using an equation described firstly by A V Hill in 1909 and then in 1910) and propose a model to explain drug-mediated receptor activation. So far, nearly all of the quantitative theoretical modelling of receptor function has centred on ligand-gated ion channels and GPCRs.
==History==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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